A Comprehensive Hepatitis C Viral Kinetic Model Explaining Cure
نویسندگان
چکیده
منابع مشابه
A comprehensive hepatitis C viral kinetic model explaining cure.
We propose a model that characterizes and links the complexity and diversity of clinically observed hepatitis C viral kinetics to sustained virologic response (SVR)-the primary clinical end point of hepatitis C treatment, defined as an undetectable viral load at 24 weeks after completion of treatment)-in patients with chronic hepatitis C (CHC) who have received treatment with peginterferon alph...
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Since the discovery of the hepatitis C virus in 1989, many epidemiological data have been acquired, especially in Europe. Treatments have showed substantial improvement over the past 25 years and have taken a great leap forward with the development of the direct antiviral agents (DAAs). However, the burden of hepatitis C remains important in Europe with more than 5 million individuals living wi...
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Hepatitis C is caused by the hepatitis C virus (HCV) infection. According to World Health Organization data, 3% of the world population (approximately 170 million people) is infected with HCV; in Poland there are over 700,000. Over 70% of those infected manifest no symptoms in the acute phase of the disease, and in about 70-80% the acute phase progresses into a chronic form. Patients with sympt...
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ژورنال
عنوان ژورنال: Clinical Pharmacology & Therapeutics
سال: 2010
ISSN: 0009-9236,1532-6535
DOI: 10.1038/clpt.2010.35